MMI8Q

Prompt

1.14.13.113

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor, and incorporation of one atom of oxygen. FAD-dependent urate hydroxylase.

AI Generated Sequence

293 AAs
MKKIVVVGGGFAGVELAGELAKKLGKKDYDITLVDRNNYHFQTPMLHQVATGTIESRSIDEPFRGHLKRQHNFHFQLGEVTDIDREAKKIQLAGEDEVTYDYLVIAVGSQTNNFGIPGVKEHAIGLKSVEDALKIRHHVLQNFEKAYPLTTDEERKKLLNFAIVGGGATGVELAGELADIVKDLLPKDYPNIDKNLMNITLIEAGDRILAAMPEKISAYAHEKLKEMGVEVLTNAMVTSYEGDGVKTKDGKEIATDMTVWATGVQASPVMKDLGLETDNRGRVLVDENLQVSG

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT93.3
NLMSIM75.0
AACOMP92.2
Seqdif (SeqID)52.3 (WP_208227131.1)
Structdif (F-Target)6.9 (5kmq C)

ProtNLM

NameScore
FAD-dependent oxidoreductase0.273
NADH dehydrogenase0.241
NAD(P)/FAD-dependent oxidoreductase0.222
Pyr_redox_2 domain-containing protein0.058
Pyridine nucleotide-disulfide oxidoreductase0.057
1.6.99.30.043
Designed by MP, using an AMD MI250 GPU