MM34X

Prompt

1.2.1.12

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).

AI Generated Sequence

334 AAs

MAKVKVGINGFGRIGRLVFRAIQEFGDIEVVGINDFIDPDYLAYMLKYDSTHGRFKGTVEVKDGKLIVNGKKIRFTAEKDPANLKWNEVGADYVVESTGVFTTTETAQKHLKGGAKKVVMSAPSADATPMFVYGVNHKTYAGQDIVSNASCTTNCLAPLAKVINDNFGIVEGLMTTVHATTATQKTVDGPSNKDWRGGRGIAANIIPSSTGAAKAVGKVIPSLNGKLTGMSMRVPTSDVSVVDLTVELEKAASYDEIKAAVKAASEGELKGVLGYTEDAVVSTDFLGDTRTSIFDAKAGIALDPTFVKLVSWYDNEWGYSNKVLDLIAHMASKD

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	87.7
NLMSIM	85.0
AACOMP	91.1
Seqdif (SeqID)	17.0 (MCB8948763.1)
Structdif (F-Target)	3.3 (4mvj B)

ProtNLM

Name	Score
Glyceraldehyde-3-phosphate dehydrogenase	0.523
1.2.1.-	0.428
1.2.1.12	0.028
Glyceraldehyde-3-phosphate dehydrogenase A	0.012
Type I glyceraldehyde-3-phosphate dehydrogenase	0.002
NAD-dependent glyceraldehyde-3-phosphate dehydrogenase	0.001