MM2XV

Prompt

1.2.3.13

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With oxygen as acceptor. 4-hydroxyphenylpyruvate oxidase.

AI Generated Sequence

409 AAs
MGPFEHAPAGLDGFEFVEFAAPDPGALEPIFERMGFTAVARHRSKDVELYRQGEINFIVNYEPDSPARYFAAEHGPSACGMAWRVRDAHKAYDRAVELGAQPVDIETGPMELNLPAIKGIGGSPLYFIERFGEGKSIYDADFEYLGEVDRHPVGAGLKYIDHLTHNVYRGRMAYWAGFYEKLFNFREIRFFDIEGEYTGLTSKAMTAPDGLIRIPLNEESKGGAGQIEEFLMKFNGEGIQHIAFGCDDLLDGWDKLKGAGMRFMTAPPDTYYEMLEGRLPGHGEPVDELQGRGILLDGTSVDGEKRLLLQIFSETVMGPVFFEFIQRKGDDGFGEGNFKALFESIERDQIRRGVLTTDEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT86.8
NLMSIM70.0
AACOMP87.1
Seqdif (SeqID)17.1 (WP_010223608.1)
Structdif (F-Target)3.0 (1cjx D)

ProtNLM

NameScore
4-hydroxyphenylpyruvate dioxygenase0.821
1.13.11.270.154
4-hydroxyphenylpyruvate dioxygenase,0.002
4-hydroxyphenylpyruvate dioxygenase and related hemolysins0.001
Hemolysin0.001
4-hydroxyphenylpyruvate dioxygenase 10.001
Designed by MP, using an AMD MI250 GPU