MM19U

Prompt

1.14.13.2

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor, and incorporation of one atom of oxygen. 4-hydroxybenzoate 3-monooxygenase.

AI Generated Sequence

285 AAs
MRTQVAIIGAGPSGLLLGQLLHRAGIDTIILERKTPDYVLSRIRAGVLEQGMVDLLREAGVSERMDAEGLVHDGIELAFDGKQHRIDLKGLTGKTVTVYGQTEVTRDLYNAREAAGGTLIYEAENVQIHDLKGSKPYVTYEKDGETHRLDCDYIAGCDGFHGVSRQSIPASALKEYIKVYPFGWLGLLSDTPPVHEELIYANHSRGFALCSMNSTLRSRYYIQVSLTDKVENWSDERFWTELKRRLPEELAERLVTGPSIEKSAIPLRSFVVEPMQYGRLFLVGD

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT90.0
NLMSIM95.0
AACOMP94.3
Seqdif (SeqID)20.3 (WP_215372730.1)
Structdif (F-Target)2.0 (1dob 2)

ProtNLM

NameScore
4-hydroxybenzoate 3-monooxygenase0.467
1.14.13.20.460
P-hydroxybenzoate hydroxylase0.043
4-hydroxybenzoate hydroxylase0.011
P-hydroxybenzoate 3-monooxygenase0.005
FAD_binding_3 domain-containing protein0.001
Designed by MP, using an AMD MI250 GPU