MLWKS

Prompt

1.1.3.38

Oxidoreductases. Acting on the CH-OH group of donors. With oxygen as acceptor. vanillyl-alcohol oxidase.

AI Generated Sequence

921 AAs
MKLTGTKYGCGGGGCGACTVMVSRYEPASKKIRHYSANACLLPICSLHGAAVTTVEGVGSTKTRVHPVQERLAKCHGSQCGFCTPGMVMSMYALLRNHPEPTSEQMTAALAGNLCRCTGYRPILDACKTFCKESICCQRKGNGKCCLDQEDLDLFDKEEKVSTRLFSSDEFLPLDPTQELIFPPELMRMAENQPKKTLVFHGERMTWISPVSLDELLDLKAAHPKAPLVVGNTGVGPEMKFRGVFHPVLIAPARIPDLNVVKCTDDGLTLGAACSLSLVKDILTNAISEFPEEKTRVFCAVLQQLRTLGGEQIRNVASLGGNIISRKSTSDLNPVLAASNCMLNLASRGRRQIPLSDIFADGVGCNTITPEEILVSIHIPYSRKGEYVSAFRQAPRRENALPITNAGMRVLFEEGTDIIKDLSIFYGGVASTTVCANQTCWTLTGRHWNEQMLDEACRLVLKEIALPGSAPGGMVDYKKTLCVSFFYRFFLEVSQSLKTMDPCHYPGIPMEYESVLQDFHTRMPQSIQIYQACKPSQPPQDPVGRPIMHQSGIKHATGEAVYCDDLPSVDGELFLAAVTSSRAHAKIVSIDTSEALKGPGVFDIITAHDVPAANEFYYSDDPEIIFARNEVICVGQIVCAVVADSDVHAKQAAAKVKVEYEVLEPVILTIEDAIKHNSFFKPKRKLEQGNVDEAFETVDNILEGEICIGGQEHFYMETQSVLAVPKGEDKEMDIYVSTQHPAIIQEMVATSLGVPANRIMCHVKRVGGAFGGKILKGGLLASICAVAANKTNRAVRLVLSRGEDMLITGGRHPFIGKYKVGFMNDGRITAADAKIYINGGCTPDESVLVAEVSLLKMDNAYKIPNLRCWAYVCKTNLPSNTAFRGFGFPQSGLVTETWITDVADKTGLSPEKIREINMYKE

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT85.2
NLMSIM85.0
AACOMP95.9
Seqdif (SeqID)8.7 (XP_050755792.1)
Structdif (F-Target)7.0 (7orc B)

ProtNLM

NameScore
AOXA oxidase0.647
Aldehyde oxidase 10.165
Aldehyde oxidase0.112
1.2.3.10.046
1.17.3.-0.002
Xanthine dehydrogenase0.002
Designed by MP, using an AMD MI250 GPU