MLV8J

Prompt

1.6.3.2

Oxidoreductases. Acting on NADH or NADPH. With oxygen as acceptor. NAD(P)H oxidase (H2O-forming).

AI Generated Sequence

499 AAs

MKNWIVNEGISIFILLWLGLNIFLFGKTYLIYDEKDKYFYTREMLGSTLAVARASADCLNFNCALILLPVCRNLLSFLRGTSRFCTRRLRRQLDKNLTFHKTVAYMICIHTVIHTIAHLFNVERYVNANQANFSGLSAALSDLGDKPNESYLNPIRTINPNTIYVVLFTTIAGLTGVVITLCLVMIITSSTEFIRRSYFEVFWYTHHLFVIFFIGLAIHGAGRIVRGQTPESLALHPVTCCKDHFEEWKKIPTCPIPQFAGNVPMTWKWVLGPMVLYLCERLVRFWRSYQRVVITKVVTHPSKVLELQMKKKGFKMEPGQYIFVNCPAVSFLEWHPFTLTSAPEEDYFSVHIRIVGDWTEGLFKACGCDKFQEAWSLPRIAVDGPFGTASEDVFSYEVVMCVGAGIGVTPFASILKSIWYKCYNANTNLRLTKVYFYWLCRDTHAFEWFADLLSALETDMQERGNMDFLTYNIYLTGWDESQANHIAVHHDEDKDVITG

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	86.2
NLMSIM	70.0
AACOMP	93.2
Seqdif (SeqID)	24.2 (ELK07153.1)
Structdif (F-Target)	13.9 (8gz3 B)

ProtNLM

Name	Score
Cytochrome b-245 heavy chain	0.511
FAD-binding FR-type domain-containing protein	0.131
Cytochrome b-245 heavy chain-like	0.083
NADPH oxidase 3	0.048
NADPH oxidase 1	0.043
Cytochrome b-245 beta chain	0.015