MLR55

Prompt

3.5.4.27

Hydrolases. Acting on carbon-nitrogen bonds, other than peptide bonds. In cyclic amidines. methenyltetrahydromethanopterin cyclohydrolase.

AI Generated Sequence

321 AAs

MSSLNELAQPLVERMIADADRLNLTVHELDGGRTVIDAGVRAPGSYEAGLRLAEICMGGLGNVVAIGPMTGSHWPLATVHVHSHPDVIACLGSQFYAGWSLSQGKYFGMGSGPARALALPKELYEEINYRDDSDFAVVLLESERPPSESVHEKVAEDCGVKPEKLTFVYAPTQSLVGAVQIVARVLEVTAYKHCAEYFDVHRIVDTGAGSPIPSPPHDFIQAMGRNTDAILYGGRVNLWVDGKDADALEEFADKLPSSTSKDHGKPFAEIFKANAGDFYKIDPKLFSPAEVITVNDVTGGRTYRAGQLNRETLLRSLGLSG

Ligand/Cofactor

methenyltetrahydromethanopterin

CC1C2C(N(C=[N+]2C3=C(N1)N=C(NC3=O)N)C4=CC=C(C=C4)CC(C(C(COC5C(C(C(O5)COP(=O)([O-])OC(CCC(=O)O)C(=O)O)O)O)O)O)O)C

Validation Metrics

PLDDT	84.3
NLMSIM	85.0
AACOMP	95.7
Seqdif (SeqID)	46.1 (WP_109122201.1)
Structdif (F-Target)	4.7 (4fio C)

ProtNLM

Name	Score
Methenyl-H4MPT cyclohydrolase	0.451
Methenyltetrahydromethanopterin cyclohydrolase	0.322
3.5.4.27	0.208
Methylene-tetrahydromethanopterin dehydrogenase	0.001
Methenyltetrahydrofolate cyclohydrolase	0.001
Methenyl phosphoribosylaminoimidazolecarboxamide formyltransferase	0.000