MLKOB

Prompt

1.20.4.4

Oxidoreductases. Acting on phosphorus or arsenic in donors. With disulfide as acceptor. arsenate reductase (thioredoxin).

AI Generated Sequence

105 AAs
MSTITVTDASFETELKSSGPVVVDFWAEWCGPCRMIAPILEELAAEYDGKVKVAKVNTDENPQTAAKYGIRSIPTLLLFKDGEVVDQRVGARPKAALAEFIDANI

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT91.5
NLMSIM70.0
AACOMP92.3
Seqdif (SeqID)26.4 (4ULX_A)
Structdif (F-Target)2.8 (4ulx A)

ProtNLM

NameScore
Thioredoxin0.993
Thioredoxin 10.002
Thioredoxin TrxA0.001
Thioredoxin domain-containing protein0.001
Thioredoxin-10.000
Thioredoxin (TrxA)0.000
Designed by MP, using an AMD MI250 GPU