MLGRL

Prompt

1.14.11.12

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors. gibberellin-44 dioxygenase.

AI Generated Sequence

295 AAs
MVEELPVIDLSKLIDGDPERDKVMELIKDACEEWGFFQVVNHGIPLELMDKVKEVTKEFFALPQEEKQKYAMTDASKVEGYGSSFLQNEVKGLEWRDYFFFRHYPPDSRIDYSRTMEEYSKELKKLAEKLLELLSENLGLEKGYLKEAFYGKGPGQLKINHYPPCPQPDLATGLEPHTDAGGITILLQDDQVSGLQVLKDGKWIDVPPIPNALVINIGDQLEILSNGRYKSVLHRVVANKDTPRISIASFLNPPPDAVIYPPPELVDEENPALYKKFTKDGEEVYRVKFRPPIAI

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT84.9
NLMSIM75.0
AACOMP90.8
Seqdif (SeqID)42.9 (QEI21528.1)
Structdif (F-Target)12.6 (5gja H)

ProtNLM

NameScore
Fe2OG dioxygenase domain-containing protein0.599
1.14.20.60.040
1.14.11.610.031
Oxoglutarate/iron-dependent dioxygenase0.020
Flavanone 3-dioxygenase0.020
1-aminocyclopropane-1-carboxylate oxidase0.014
Designed by MP, using an AMD MI250 GPU
EC Repo - MLGRL | 310.ai