MKVLG

Prompt

1.1.1.57

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. fructuronate reductase.

AI Generated Sequence

499 AAs

MKQLNAELLAQQRAALPANVSPGYDRSALRAGIVHLGFGAFHRAHQAVYTDHLFNHAGSDWGICEVNLLPGDERLVDQLQAQDHLYTVAEMADDQWQARIVGSMKEALHAPDGPGEAILAKMAHPQTRIVSLTITEKGYYCDPATGELLQHPAIVHDLANPAKPSAIGLIVEGLRRRRQAGLKPFTVMSCDNMPENGHVTRLAVLGFARLQDPALAAWIDENVCFPNTMVDRIVPATTPETLDKIAATFGVCDPWAVACEPFRQWVIEDNFVAGRPAWEKVGAQMVADVVPFEQMKLRMLNGSHSALAYLGYLAGYDHICDAMADPHYRRAALALMNEQAPTLAPVDGVDLQQYADSLIERFSNPALKHRTWQIAMDGSQKLPQRMLPSIRWHRAQGSFDHCLALAVAGWMRYVGGVDEQGNAIDVRDPLLAEIKAVVSSQGDGARVAALLSIPAIFGDDLPDNPRFVAAVTQAYQSLHANGANRTVVEHVKQHGALAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	91.0
NLMSIM	70.0
AACOMP	92.3
Seqdif (SeqID)	32.4 (WP_105648116.1)
Structdif (F-Target)	5.2 (7rk5 B)

ProtNLM

Name	Score
Mannitol dehydrogenase family protein	0.378
Fructuronate reductase	0.267
D-mannonate oxidoreductase	0.089
1.1.1.57	0.068
Mannitol dehydrogenase domain protein	0.053
Polyol:NADP oxidoreductase	0.025