MKRJA

Prompt

1.1.1.30

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 3-hydroxybutyrate dehydrogenase.

AI Generated Sequence

486 AAs

MSLSGKTAVVTGGNSGIGLAIARALAARGANVVLNGFGDEAAETVRREIEAAGAKAYHHGADMSKPESIEAMIDFAVEEFGGVDILVNNAGIQHVKPIEDFPVEKWDAIININLSGAFHTTRHALPGMKKQGWGRIINIASVHGLVGSPFKSAYVAAKHGILGLTKSVALEGAKYGITTNAICPGYVRTPLVEKQIPDVAKEIMLGKQVPKTFVTVEQVATLVFLLCSPASSNITGQAWIIDGGWTARHGGATTHVYDEKLLGWAKEVAKENGLDPSLLTKQQMDLMAKRVAEFGLSPLNDHVGMVVHGVKEIGGLDVLINNAGIQHVKPIEDFPVEKFDAIISINLLSGAFHTIRHALPGMKKRGWKGRIINIASVHGLVGSPFGKAAYVAAKHGIVGLTKTVALEGAENYGITTNAICPGYVRTPLVEKQIPDVVKEVMLDKQPNKEFVTVEQVATLVFLLCSPASSQITGQAWIIDGGWTARK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	86.0
NLMSIM	90.0
AACOMP	92.4
Seqdif (SeqID)	42.1 (MCF8495097.1)
Structdif (F-Target)	2.4 (2uvd C)

ProtNLM

Name	Score
3-hydroxybutyrate dehydrogenase	0.605
1.1.1.30	0.259
D-beta-hydroxybutyrate dehydrogenase	0.073
Cytochrome C biogenesis protein CcmE	0.003
Short-chain dehydrogenase/reductase SDR	0.003
SDR family oxidoreductase	0.002