MKPY1

Prompt

1.13.11.15

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. 3,4-dihydroxyphenylacetate 2,3-dioxygenase.

AI Generated Sequence

325 AAs

MAKIAGLATSTHVPLINAAEEDGYDEHVKGFEAAREWLKEQKPDVVVIVYDNHGVSFFFDMYPTFAIGHAAEYAEGGGVRPYPIEGDPELAEHIAKQLVDQDFDITCYDEMKLDHGFTSPLLMLYGEGDWKPVIPLSVNVVQAPLPSPKRCYALGKGIARAIESWPEDLRVAIVATGGLSHQLQGPRAGFENEDWDKNFLELIRNDPEDFLELTHEDYINAAGSEGGEILWTLAMRGALNEGVTHVENSYYVPASNTMGAMNIFEYSKPENAERFAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	85.2
NLMSIM	60.0
AACOMP	84.4
Seqdif (SeqID)	50.4 (MDX1780565.1)
Structdif (F-Target)	12.6 (1bou D)

ProtNLM

Name	Score
LigB domain-containing protein	0.223
1.13.11.8	0.136
Protocatechuate 3,4-dioxygenase	0.103
Protocatechuate 4,5-dioxygenase beta chain	0.062
2,3-dihydroxyphenylpropionate 1,2-dioxygenase	0.038
Extradiol ring-cleavage dioxygenase	0.025