MKP2N

Prompt

6.3.4.13

Ligases. Forming carbon-nitrogen bonds. Other carbon--nitrogen ligases. phosphoribosylamine--glycine ligase.

AI Generated Sequence

473 AAs

MNILLLGSGGREHALAWKLAQSPLLDKLFAAPGNPGIAEVAECVALDVEDHAAVVAFCRENAIDLVVVGPEAPLVAGIADRLRAAGIAVFGPSAAAAQLEGSKGFTKDLCAAAGAPTAAYARFTDAAAAKAYVRAQGAPIVVKADGLAAGKGVTVAMTLDEALAAVDDCFGGAFGAAGAEVVIEEFMEGEEASFFCLCDGTTALPLATAQDHKRVGDGDTGPNTGGMGAYSPAPVMTPEMIERTMREIIEPTVRGMAERGHPFQGVLYAGLMITADGPKLIEYNVRFGDPECQVLMMRLKSDLLPLLLAAADGTLAEVSVEWRDDAALTVVMAAKGYPGAPEKGTVIRGLDAAEAEDGVMIFHAGTALKDGALVATGGRVLNVTARGATVAEAQARAYAAVDRIDWPEGFCRRDIGWQAVAREAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	94.7
NLMSIM	85.0
AACOMP	80.4
Seqdif (SeqID)	19.3 (MBT9368861.1)
Structdif (F-Target)	2.5 (2xd4 A)

ProtNLM

Name	Score
Phosphoribosylglycinamide synthetase	0.209
6.3.4.13	0.208
Phosphoribosylamine--glycine ligase	0.194
Glycinamide ribonucleotide synthetase	0.179
GARS	0.162
Phosphoribosylformylglycinamidine cyclo-ligase	0.008