MKM35

Prompt

1.1.2.4

Oxidoreductases. Acting on the CH-OH group of donors. With a cytochrome as acceptor. D-lactate dehydrogenase (cytochrome).

AI Generated Sequence

289 AAs
MTDNKALIDRLADIVGRDHVLTGDAATERYRRGFRFGEGRVLAVVRPGTLVEHWRVLQACVDADCIILMQAANTGLTGGSTPDGNDYDRPVVIINSRRLDKLHVINDGRQVVCLPGATLYDLEKVLKPLGREPHSVIGSSCIGASVFGGVCNNSGGALVRRGPAYTEMALFARIDEDGRLELVNHLGIDLGDTPEEILTRLEDGRYDAADVRHDDRHASDHDYCRHVRDVDADTPARFNADPSRHYEASGCAGKLMVFAVVRDTFEAEKNQVFYIGSNDPADVTELRRH

Ligand/Cofactor

D-lactate

CC(C(=O)O)O

Validation Metrics

PLDDT76.2
NLMSIM75.0
AACOMP90.8
Seqdif (SeqID)29.0 (EHV2074356.1)
Structdif (F-Target)14.8 (1f0x B)

ProtNLM

NameScore
D-lactate dehydrogenase0.585
1.1.1.280.300
D-LDH0.037
Lactate dehydrogenase0.019
Quinone-dependent D-lactate dehydrogenase0.016
FAD-binding PCMH-type domain-containing protein0.007
Designed by MP, using an AMD MI250 GPU