MKK2J

Prompt

2.5.1.61

Transferases. Transferring alkyl or aryl groups, other than methyl groups. Transferring alkyl or aryl groups, other than methyl groups. hydroxymethylbilane synthase.

AI Generated Sequence

308 AAs
MTDRPLRIGTRGSPLALAQAHEVRARLAAAHGLPEAEIVPMRTRGDRIQDRPLAEIGGKGLFTKELEQALLDGRIDIAVHSMKDMPTQLPEGLELSAFLPREDARDAFISNAAATLADLPQGARVGTSSLRRQAQLLRLRPDLDIVEFRGNVQTRLAKLDEGVADATILAAAGLKRLGLADRITDLLDPETWLPAPGQGAIGIECRAGDTRIDALLAAIDHAETAAAVAAERALLAALDGSCRTPIAGLAELRGDELRLRGLVLTPDGSQLLRAEATGPAADAEALGRALAEELLARGAPEFFAERAA

Ligand/Cofactor

FPP

CC(=CCCC(=CCCC(=CCOP(=O)(O)OP(=O)(O)O)C)C)C

Validation Metrics

PLDDT94.7
NLMSIM60.0
AACOMP86.0
Seqdif (SeqID)31.9 (HUF55891.1)
Structdif (F-Target)2.0 (5h6o A)

ProtNLM

NameScore
Porphobilinogen deaminase0.201
Pre-uroporphyrinogen synthase0.189
PBG0.188
HMBS0.154
2.5.1.610.143
Hydroxymethylbilane synthase0.122
Designed by MP, using an AMD MI250 GPU