MKJQK

Prompt

5.4.99.13

Isomerases. Intramolecular transferases. Transferring other groups. isobutyryl-CoA mutase.

AI Generated Sequence

500 AAs

MTDLSKYTPKNHIRFVTAASLFDGHDASINIMRRIIQSTGVEVIHLGHNRSVEEVVNAAIQEDVQGIAISSYQGGHIEYFKYMVDLLKEKGAGHIKIFGGGGGVILPSEIKELHDYGIARIYSPEDGRKMGLQGMINDMVKRSDFPTPKELNGELDKLSGDNIRAIARLISLAENFKDEKSVQELKEKWNEKNKIPVLGITGTGGAGKSSLTDELVRRFLESFEDKKIAILSIDPSKKKTGGALLGDRIRMNAIHNSRVYMRSLATRDANLALSKHIADAIDVVKLAGYDLIIVETSGIGQGDTEITEHSDLSMYVMTSEFGAPTQLEKIDMLDFADFIAINKFEKRGAEDALRDVQKQYQRNHLDWETPEEKMPVYGTIASQFNDPGPNTLYAAIIEKINEKTNADWKTEFTITEKTEKKVFIIPGERVYYLAEITERVNKYNEWTKKQAELARKLFQLETIIESLKENNLDEEKIEELEKIYDKVKSELTENTKEILE

Ligand/Cofactor

acetyl-CoA

CC(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O

Validation Metrics

PLDDT	83.8
NLMSIM	80.0
AACOMP	91.1
Seqdif (SeqID)	34.2 (HAA11701.1)
Structdif (F-Target)	16.7 (4xc8 B)

ProtNLM

Name	Score
Fused isobutyryl-CoA mutase	0.270
Isobutyryl-CoA mutase	0.152
ICM	0.131
5.4.99.13	0.127
P-loop GTPase	0.123
G-protein chaperone	0.092