MKCST

Prompt

2.2.1.1

Transferases. Transferring aldehyde or ketonic groups. Transketolases and transaldolases. transketolase.

AI Generated Sequence

500 AAs
MTTTTLDLDLANAIRALAMDAVEAAKSGHPGTPMGMADIATVLFQRHLRHDPANPDWADRDRFVLSAGHGSMLIYALLHLTGYALPLDDIKAFRQLGSKTAGHPENGHTAGVEITTGPLGQGLANAVGMALAERHLAARFNPDGLPVDHHTYVIAGDGCLMEGISHEAISLAGHLKLGKLIVLYDDNHITIDGPVELSTSTDQVARFEAYGWHVIRVDGHDVAAIAAAIEAAQASDRPSLIACKTIIGFGAPNKQGTEKVHGSALGADEIALTRKFLGWTHEPFEIPADVLAAWKAAGERGAAAHAAWQARFAAAPERAALERRMAGELPAGFAAALAPYKAELAAGAKTVATRKASEMALEVINAVLPETVGGSADLTGSNLTKTKGLKSITPADYAGRYIHYGIREHGMAAAMNGIALHGGLIPYGGTFLVFSDYCRPAIRLAALMGIRVIYVMTHDSIGLGEDGPTHQPVEHLASLRAIPNLDVFRPADAVETAECW

Ligand/Cofactor

thiamin pyrophosphate

CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCOP(=O)(O)OP(=O)(O)[O-]

Validation Metrics

PLDDT92.5
NLMSIM70.0
AACOMP90.2
Seqdif (SeqID)27.0 (MPZ09450.1)
Structdif (F-Target)3.0 (1qgd B)

ProtNLM

NameScore
Transketolase0.524
2.2.1.10.473
Transaldolase0.000
Transketolase 10.000
1-deoxy-D-xylulose-5-phosphate synthase0.000
Acetolactate synthase0.000
Designed by MP, using an AMD MI250 GPU