MK0LX

Prompt

1.5.1.6

Oxidoreductases. Acting on the CH-NH group of donors. With NAD(+) or NADP(+) as acceptor. formyltetrahydrofolate dehydrogenase.

AI Generated Sequence

901 AAs

MKIAVIGQSLFGQEVYNALRKEGHEVVGVFTIPDKDGKADPLAVEAKKDGVPVFKFPRWRVKGQAIPEVVEAYKAVGAELNVLPFCSQFIPMEVIDAPKHGSIIYHPSLLPRHRGASAINWTLIHGDKIGGFSIFWADDGLDTGPILLQKECDVEPNDTVDSLYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEGIQKKENAKIDWNQPAEAIHNWIRGNDKVPGAWTECDGQKVTFYGSTLNGGSVPAGQPLEIAGASRPGVVTKNGLVLFGNDGKALLVRNLQFEDGKMIPASKYFSGDSSAVELTEEEKAMAEAIRAVWKGILSNVAPIEDSTDFFKSGAASMDVVRLVEEVKQRCDGVQLQNEDVYMATTFADFIQMVVRKLRGEDQEGELVIDYVSKEVNNMTVKMPHQLFINGEFTDAENGKTYDTINPTDGSVICKVSLAQVNDVDKAVAAAKEAFENGEWGKMNARDRGQLMYRLADLMEEHQEELATIEAIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPIGVCGIIIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTALKFAELTVKAGIPKGVINILPGSGGLVGQRLSDHPDVRKLGFTGSTEVGKHIMKSCAVSNVKKVSLELGGKSPLIIFADCDMDKAVRMGMSSVFFNKGENCIAAGRLFVEESIHDEFVRRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLDKLLEYCQKGVKEGATLVYGGRQVDRPGFFMEPTVFTDVEDHMFIAKEESFGPVMVISKFKDGDVDGVLARANDTEYGLASGVFTRDINKAMYVSEKLEAGTVFVNTYNKTDVASAFPGGFKQSGFGKDLGEQALNEYLKTKAVTIEY

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	89.1
NLMSIM	90.0
AACOMP	93.9
Seqdif (SeqID)	13.3 (XP_042259274.1)
Structdif (F-Target)	2.0 (7a6q B)

ProtNLM

Name	Score
10-formyltetrahydrofolate dehydrogenase	0.513
1.5.1.6	0.404
Formyltetrahydrofolate dehydrogenase	0.045
Methylenetetrahydrofolate dehydrogenase	0.004
Aldehyde dehydrogenase 1 family member L1	0.003
Cytosolic 10-formyltetrahydrofolate dehydrogenase	0.002