MJM0B

Prompt

4.2.1.76

Lyases. Carbon-oxygen lyases. Hydro-lyases. UDP-glucose 4,6-dehydratase.

AI Generated Sequence

664 AAs

MASYPKNYILITGGAGFIGAHVANRLIREYPDYKIVVLDKLDYCGNLKNLVSVKNSPNYKFVKGDIASADLVNFLITEHEIDTIMHFAAQTHVDNSFGNSFEFTKTNIYGTHVLLEACKVTGQIKRFIHVSTDEVYGETDDAVGNNEEASQLLPTNPYSATKAGAEMMVMAYGRSYGLPVITTRGNNVYGPNQFPEKLIPKFILLAMQGKPLPIHGDGSNVRSWLYCEDVAEAFEVILHKGEVGHVYNIGTKKERRVIDLAKDICKLMDKDPESSIKYVENRPFNDQRYFLDDSKLQNLGWSERTTWEEGLRKTIEWYTNNPDWWGDVSGALLPHRRMLMMPGEERESEGVSEKTESSSTESSSETSVMVPKSITEKIGKSSKLVFIYGRTGIWGGLGGKLKECKQIPYEYGRGELLDADGRLAKVQKPTHVFNAAGTWTGKPNVDWCESHKPETIRNVVGTGLNLADVCKNEGLFIMNPYATGICFEYDKNPNFQGSFYSKTKAMVEELLKEYANVCTLRNRMPISDWLNNPRNFITKIRNGYQKITPRYKVVNIFPNMVTLMDELIPISIEMAKNCRGIWNFTNPGPVVSHNEILEMYKKYIDPDFKWENFTFEEQKAKVIAPRSENNMDAKSLKKEFPELISMKEKIKEIFENPKNPISKN

Ligand/Cofactor

UDP-glucose

C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OC3C(C(C(C(O3)CO)O)O)O)O)O

Validation Metrics

PLDDT	76.5
NLMSIM	60.0
AACOMP	91.6
Seqdif (SeqID)	25.5 (XP_059282853.1)
Structdif (F-Target)	4.2 (2hun B)

ProtNLM

Name	Score
DTDP-glucose 4,6-dehydratase	0.359
4.2.1.46	0.274
NAD(P)-bd_dom domain-containing protein	0.089
Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1	0.030
DTDP-D-glucose 4,6-dehydratase	0.027
Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1-like	0.026