MJLK0

Prompt

1.14.13.8

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor, and incorporation of one atom of oxygen. flavin-containing monooxygenase.

AI Generated Sequence

499 AAs
MKKIAVIGGGAAGSLAAAKCLQEKGLEPVEFERENDIGGSWLFTPPLEDVRASVLESRTNSIPERMMCFSDFPIPEDRPNFVNHKEIEKYIKLFAEHFDLDDYHLVTTGSVTRTNFPDGVEGWQVKTETNEGQELINKFVDMVVCAGHHTEPLPLPELPGFNIFTGQHTSHYEYKAGEEFAGKNVLVVGIGNTGSDIAISLVEGAKRVLLSTSRGSVWANERILERGVKVDVLMTRMVSCVEDNVTVKDGKEIIPKPLNAWFGHRPGLPPKHKGLMEKRNVLDDVPNRLICGDIKVDGKVEATAGSVEFEDGTVPEEADAVIFATGYKANFPFLKEGSVVEKNIPYNYLKYMVPNLGNKTALAVLGLFPLTGLAMFTEAQARWYARQVFRNKSRLSRDNMWNMIFDKKRNARRIVVPKSRHTLQLDNFIDWIDELAEIIGARPDLLWLFLTDPRLKVKMFFGCPTPYQWRLQGPGKWEGARQAILTQWDRVIKPVKTRV

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT77.5
NLMSIM60.0
AACOMP94.1
Seqdif (SeqID)53.8 (UZZ64696.1)
Structdif (F-Target)7.8 (6sek B)

ProtNLM

NameScore
1.14.13.80.540
Dimethylaniline monooxygenase [N-oxide-forming]0.397
Flavin-containing monooxygenase0.012
Dimethylaniline oxidase 10.008
Dimethylaniline monooxygenase (N-oxide forming)0.006
Dimethylaniline oxidase 50.006
Designed by MP, using an AMD MI250 GPU