MJH63

Prompt

1.3.5.2

Oxidoreductases. Acting on the CH-CH group of donors. With a quinone or related compound as acceptor. dihydroorotate dehydrogenase (quinone).

AI Generated Sequence

415 AAs

MSLRLSIPGLELKNPIIAASGTFGFGREYGELFDLSRLGGSITKLTTLEPRFGNPTPRMAETGGGMNACIGLQNPGLEGFVEELKPWLERQFDNPIIANVAGRVEDEYAVVARKLSDAGVEAVENLNSCPNVKGGGINIGQNPEAAEDLTRAVKDVSDVPVYKLSPNVTDIVSMATALENAGADGFSLLTILKGMRLDLKTRRPALANKTGGLSGAIKPLAVERMVWDVAQAVKIPIIGMGIVNTADRALEILAAGASAVQVGTANFVDPLASPEVIRGLERRLDELGIDRIGEIVGSAHDTRPRIRGASAVQVYTGAVYEGPGLVDDICKALADLCRRDGFGAIADALGHDTKLDADAPALLAARRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT	84.1
NLMSIM	70.0
AACOMP	87.2
Seqdif (SeqID)	39.2 (MBQ3389677.1)
Structdif (F-Target)	5.4 (1ep2 2)

ProtNLM

Name	Score
DHOdehase	0.247
Dihydroorotate dehydrogenase	0.201
1.3.-.-	0.196
DHODase	0.189
DHOD	0.147
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit	0.004