MJE6H

Prompt

1.14.19.36

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. sn-1 acyl-lipid omega-3 desaturase (ferredoxin).

AI Generated Sequence

497 AAs

MGGVKVYDIPEHIEHYKPVTFWEDCIKHYNGDDQLVVIDERVYCITIWAERPHGGERIRSLHGEGDATEFLANHHLSKPWVTKKMKALPLPGAAEWVGPDGKLKYLQEKFDRGLERKITEEGTLKPKPDLFGLYLLGHVLMLSEAVWLLVLYLGSGLIPTLLCGVVLAATQAQAGLLHHDFGCSVFKKSWKNDMVHKVFGNGCLAGCSPAWWHNRDMQHHAKINESHKDPDVQWDLVFVVGDHQPVEYGKTKYEYPYNHQEHKFFFIGCPATLIPLYFNVRYIMTLLGKQDWWDLWGVTYFVRYYLTIYPFGGLGGALICLVVVTRMIPSWFVWTITNIGHLPMDITHEKQDWLDGQIQGTCNVDKQSFFNWFHGCLYQVGVHHLFPRMPRHNYHKVAPKVQSLCDKHGIEYVEKPLLKWMTDIVISKLKSGDLWLDAYLEEEKKKKEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	73.1
NLMSIM	75.0
AACOMP	87.5
Seqdif (SeqID)	52.1 (XP_036619296.1)
Structdif (F-Target)	23.6 (1m2i A)

ProtNLM

Name	Score
FA_desaturase domain-containing protein	0.398
Cytochrome b5 heme-binding domain-containing protein	0.137
Fatty acid desaturase	0.055
Fatty acid/sphingolipid desaturase	0.040
Delta-6 fatty acyl desaturase	0.017
Fatty acid desaturase,	0.016