MJ8XW

Prompt

6.2.1.49

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. long-chain fatty acid adenylyltransferase FadD28.

AI Generated Sequence

500 AAs

MSEEELRRYLDHRLAPLGEDGALEVRDGRRVLVRGLGGLGSAAAAYLAAAGVGRLTLVDGDVVENTNLLQVLLFGLWRAGVRPKVAATAARLAEIDPDVEVAAAERVLTAAGALDLVADADLVVDLTDDLATRYAVNAACVAHGKPHVVSAAGRWEGDVAVADWDGRPCAYLFTSGTGPPKVVACTAHGLLGTVPQVIGTLQATNEVKILTGLGPLFSGSLMFFDALAMGFRTIRLLRRPDCPAGAFLATLREHGRTEFYCVTPVTQRNLARPDVAALDYAALRTVVVGGGRVRPEVEAFIARWPGCELVNQYGMTEACPVGTGLPEDRDRHRCVGLPSGEVALRIVDRDGTPLPPGAIGEIAWRGPEVTRGYGHPRAAAEAARDGDLWRTGDVGRRDERGYLTVYGRLDEIFTVRGYEINPVEVEAVLLHAPGVADAAVVGLPDELAGEPVKAFVVTLDGATLTRPELVAHVRARLAKMPVRGEFRLVDLPRTATGKIR

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	80.9
NLMSIM	60.0
AACOMP	88.4
Seqdif (SeqID)	53.7 (HUF46684.1)
Structdif (F-Target)	6.7 (1jwa 2)

ProtNLM

Name	Score
Long-chain fatty acid--CoA ligase	0.190
AMP-binding protein	0.132
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	0.113
6.2.1.26	0.079
6.2.1.3	0.078
Long-chain-fatty-acid--CoA ligase	0.051