MJ689

Prompt

1.13.11.8

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. protocatechuate 4,5-dioxygenase.

AI Generated Sequence

462 AAs

MAKIIGGLATSHTPTIGYAFDQAKQDPAVWKPIFEAFGPIHEWLAKKKPDVLFIVYNDHVTSFFFDHYSAFTLGVTDTYQADDDGGGRRPLPPIVGHPELARHIAESLVADEFDMTMFQDKPLDHGCFSPLSMLCPNGGDWPVKVIPLQMGVLQLPVPSARRFYKLGQALRRAIESYPEDLKVAVIATGGLSHQVHGERTGFNNPEWDARFLNLLERDPEKLAAMTPQEYAELGMGEGVEIIMWLVMRGALSAKVERHRPSYYLPSMTGIATLILENHEALPEAQLAAVRARHAAQQALAEEHGVTPYSLETAGRKAYRLNTHLMHMDAPAYRRAFFAEHEARFVAEGFDAAEEAALIRADWRGLHHYGVAFFLLEKLGAAIGVSNLQIYAAWRGELGFAAFTAEVRRHRAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	78.8
NLMSIM	60.0
AACOMP	85.6
Seqdif (SeqID)	34.1 (WP_309933931.1)
Structdif (F-Target)	20.2 (3wrb A)

ProtNLM

Name	Score
Gallate dioxygenase	0.311
1.13.11.8	0.258
Protocatechuate 3,4-dioxygenase	0.125
Protocatechuate 4,5-dioxygenase alpha subunit /protocatechuate 4,5-dioxygenase beta subunit	0.054
LigB domain-containing protein	0.029
Protocatechuate 4,5-dioxygenase beta chain	0.018