MJ0II

Prompt

3.5.4.30

Hydrolases. Acting on carbon-nitrogen bonds, other than peptide bonds. In cyclic amidines. dCTP deaminase (dUMP-forming).

AI Generated Sequence

189 AAs
MSIMSDKWIRYMAEEHGMIEPFDPEQVRYNEGQRVISYGYSSYGYDVRCANEFKIFTNINSAIVDPKNFDEPSFVDVKGDVCIIPPNSFALARTVEYFRIPRDVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGVAQMLFFEASDECETSYKDRNGKYMGQRGVTLPRKT

Ligand/Cofactor

dCMP

C1C(C(OC1N2C=CC(=NC2=O)N)COP(=O)(O)O)O

Validation Metrics

PLDDT88.9
NLMSIM90.0
AACOMP91.2
Seqdif (SeqID)15.0 (UCF23750.1)
Structdif (F-Target)4.8 (4dhk A)

ProtNLM

NameScore
Deoxycytidine triphosphate deaminase0.396
DCTP deaminase0.342
3.5.4.130.257
DUTPase domain-containing protein0.001
GTP cyclohydrolase I0.001
Bifunctional dCTP deaminase:dUTPase0.000
Designed by MP, using an AMD MI250 GPU