MIVR1

Prompt

2.1.1.189

Transferases. Transferring one-carbon groups. Methyltransferases. 23S rRNA (uracil(747)-C(5))-methyltransferase.

AI Generated Sequence

428 AAs

MKCPHYDRGRCMSCHDLQQPYSQQLRATKADLHRLLPGAPVEEWLPPVSSPEHAFRNKAKMVVSGSVEPPVLGMCSHDGTPGELCDCCLYPASMAPVFPALWKFVRRAGIPPYNVDRKRGELKYILLTERSQSGEMMLRFVLRSETKLPRIERELPQLQAQPQLKVVTSVNIQPVHMAILEGETEIFLTEEQALEERFNDVPLFIRPKSFFQTPNVVAAKLYATAEDWVRDLPDIHMWDLVCGVGFGFQLHATPELQLTGIEIEAEAIACLAPSAEALGLTRLQFQALDSTAFLAKGTEVKELTVVNPPRRGIGKEIARSFSQMAPRCILYKSGCNATSMAKDLRALPFHLRVQQLDLFPRHTDHGYEVLTLLKRRDSPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP

Ligand/Cofactor

S-adenosylmethionine

C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O

Validation Metrics

PLDDT	85.6
NLMSIM	90.0
AACOMP	85.5
Seqdif (SeqID)	32.1 (WP_021550518.1)
Structdif (F-Target)	17.6 (5zq8 B)

ProtNLM

Name	Score
23S rRNA (Uracil(747)-C(5))-methyltransferase RlmC	0.338
23S rRNA m(5)U-747 methyltransferase	0.160
23S rRNA (Uracil(747)-C(5))-methyltransferase	0.125
2.1.1.189	0.063
2.1.1.-	0.054
2.1.1.190	0.038