MINN7

Prompt

2.5.1.60

Transferases. Transferring alkyl or aryl groups, other than methyl groups. Transferring alkyl or aryl groups, other than methyl groups. protein geranylgeranyltransferase type II.

AI Generated Sequence

294 AAs

MHGRIKVKTSEEQAAEKAKEREKKLKLYTQATQAVFQKRREGELDDESLELTSQLLSANPDFATLWNCRREVLLLGEQMKSPEELAALYKEELGFLESCLRVNPKSYGTWHHRCWVLGRLPEPNWARELELCDRFLELDERNFHCWDYRRMVARQAGVPAEEELAFTDSLITRNISNYSAWHYRSRLLPLLHPQPSDPGQIGEPRLGQLLPEKVLLEEWELVQNAFFTDPDDQSAWFYHRWLLGRADPQDLACRLVVSREEACLSISFEHPLVVDREMTLLLLVDEERPLAIWR

Ligand/Cofactor

PLP

CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O

Validation Metrics

PLDDT	88.8
NLMSIM	95.0
AACOMP	89.3
Seqdif (SeqID)	25.1 (AAH12214.1)
Structdif (F-Target)	22.9 (3hxd A)

ProtNLM

Name	Score
Geranylgeranyl transferase type II subunit alpha	0.348
2.5.1.60	0.332
Geranylgeranyl transferase type-2 subunit alpha	0.301
Rab geranyl-geranyltransferase subunit alpha	0.003
Rab geranylgeranyltransferase subunit alpha	0.001
Rab GGTase alpha	0.001