MIG2S

Prompt

6.2.1.45

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. E1 ubiquitin-activating enzyme.

AI Generated Sequence

998 AAs

MDDVKNIGNAEIDESLYSRQLYVLGHEAMKRMGQSNVLIVGLKGLGVEIAKNIALAGVKSLTLYDPKPVSISDLSSQFFLQPEDVGKPRDEVTVPRVAELNAYVPVKVHESGELTDTLSQLKKYQVVVLTNTPLKDQLKIGDFCHSNGIKFVIADTFGLFGSIFCDFGKNFTVIDPTGEEPLSGIVAGIDKDEGLVSVLDETRHGFEDGDYVTFTEVKGMEGLNGCEPRKIEVLGPYTFSIGDVSGLGTYQRGGLYTQVKMPKFIEFKSLQQQLKDPEFVISDFAKFDRPQQLHIGFQALHKFQEEHGRLPRPWHNEDAEEVLKIAKNIAKAEGLKVEELDEKLIKELSYQARGDLNPMAAFFGGIAAQEVLKAVSGKFHPIKQWLYFDSLESLPTSTKRSEELCKPLGSRYDGQIAVFGKEYQEKIANLTQFLVGAGAIGCEMLKNWAMIGLATGPKGEITVTDMDQIEKSNLNRQFLFRPKDVGKLKSECAAAAVQAMNPDLKGKITMLKDRVGPDTEHIFNEEFWEGLDGVTNALDNVEARTYVDRRCVFFRKPLLESGTLGTKGNTQVVIPHLTESYGSSQDPPEKSFPMCTLRNFPNRIEHTIAWAKELFETFFKQPPETVNMYLTQPNFIESTLKQAGNEKQTLETIRDYLVTEKPLTFEDCIVWARLQFEKQYNNAIKQLLYNFPKDSKTSSGTPFWSGPKRAPTPLKFDPSNPTHLDFVVAGANLHAFNYGIKGSGTDKSYIKKVLDNMIVPEFTPRSGVKIQVNDSEPDPNAQSGSFDDNEEIQKLTESLPSPKSLAGFRLTPVEFEKDDDTNHHIDFITACSNLRAENYKIEPADRHKTKFIAGKIIPAIATTTALVTGLVVLELYKIVDGKKDIEQYKNGFVNLALPFFGFSEPIASPKGEYKGIDVTIWDRFEFRGEDITLQEFLDHFKEKGLNITMISSGVSMLYSSFMPKSKLKEDRLPVKLTELVETISKKDIPDHVDVVFVK

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	87.7
NLMSIM	60.0
AACOMP	93.2
Seqdif (SeqID)	20.4 (KAF4165857.1)
Structdif (F-Target)	4.9 (6dc6 A)

ProtNLM

Name	Score
Ubiquitin-activating enzyme E1	0.238
Ubiquitin-activating emzyme E1	0.213
UBA_e1_C domain-containing protein	0.183
Ubiquitin-activating enzyme E1 1	0.127
Ubiquitin activating enzyme	0.023
Ubiquitin-like modifier-activating enzyme 1	0.017