MIF4U

Prompt

1.13.11.39

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. biphenyl-2,3-diol 1,2-dioxygenase.

AI Generated Sequence

300 AAs

MSGIRGLYHMRIEATDMAAWREYGLDVLGMVEGKGAEPGALYLRMDDFKARLVVVPGEHDRLLEAGWECANAEGLQEIRDRLDAEGTPYKEATAAEALDRRVDEMIAFSDPSGNTLEAFHGTALEHRRVVSPYGHKFVTGEQGLGHVVLTCRDDAEALHFYRDVLGFRLRDSMRLPPQLVGRPDGAPAWLHFFGCNPRHHSLAFLPMPTSGGIVHLMVEVENADDVGLCLDRALRRKVPMSATLGRHVNDLMLSFYMKTPGGFDVEFGCEGRQVMDDDWIARESTAVSLWGHDFTVGRPG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	90.1
NLMSIM	60.0
AACOMP	91.4
Seqdif (SeqID)	10.4 (WP_077585467.1)
Structdif (F-Target)	4.2 (2zi8 A)

ProtNLM

Name	Score
2,3-dihydroxybiphenyl 1,2-dioxygenase	0.313
Extradiol dioxygenase	0.148
Iron-dependent extradiol dioxygenase	0.129
1.13.11.-	0.121
3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase	0.069
Biphenyl-2,3-diol 1,2-dioxygenase	0.051