MHZ0M

Prompt

1.1.1.10

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. L-xylulose reductase.

AI Generated Sequence

500 AAs

MSRRVALVTGGSRGIGRAIARELARRGADVVVVDRDEAALRAVAAELEARGVRAVAVVPVDVADEAAVRAAVAAAAAAGGRVDVLVNNAGIMRDAPLEDMTDADWDRVMAVNLLGTFLTSRAALPLMRARGGRIVNISSVAGHRGNPFGQAYSASKAAAVGMTRTLALELARHGITVANVAPGFVRTEMLDRLGPERVAALRAHIPLGRTAEPEDVAAAVAWFAGDAASYITGQVLHVDGGLYGVRGHPVLRFDGRAAAAAAAAAAAGVDVVVVNAGIMRDGRPVEDLTPEQWDAVVAAARAAGFDLAVVVNAAGIMRDAPLEDLTPEQWDRVMAVNLLGAFFLTSRAAAPLLRARGARVVNVSSVAGHIGSPFGQANYAASKAGAVMGLTRALALELAPHGVTVANVAPGYVRTDMLAGRFGPERIAAVVAWLASDAASYVTGQNLHVDGGLTYGRGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	80.6
NLMSIM	85.0
AACOMP	82.3
Seqdif (SeqID)	45.5 (WP_068668332.1)
Structdif (F-Target)	22.6 (8hi6 2)

ProtNLM

Name	Score
SDR family oxidoreductase	0.268
Short-chain dehydrogenase	0.187
SDR family NAD(P)-dependent oxidoreductase	0.104
Short-chain dehydrogenase/reductase SDR	0.054
3-oxoacyl-[acyl-carrier protein] reductase	0.051
1.1.1.100	0.049