MHVNL

Prompt

6.2.1.11

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. biotin--CoA ligase.

AI Generated Sequence

499 AAs

MTDRLTLLDLLADGRFHSGEELGRELGVSRTAVWKHLQALRAAGLDLHAVRGRGYRLAAPDRLLDAAEIAAGLAAAGLPRAVVVHDTLPSTNAEALRRLAAAGADGVVCLAEEQTAGRGRLGRRWVSPAGANLYFSLLWRFDAPMRALAGLSLAVGVAVAEALRELGGDAAALKWPNDLLVGGRKLAGILVEMLGELDGVAHAVIGIGINVNLAAAFPADVDQPWTSLAELAGAPVDRNRLVAALLAGLEAALAAFEARGFAPFRDEWERLDALFGRPVRLLAAGRTVEGVARGVDADGALLLEVADGVERRVLGGESLREVGDGVAYGPVLRRGRRRGVARGPLVAEVALVRDEDGDVAAGRAGRVVDGPALDAAALAAAGRAVVAEDPAWRAGDLHWVADGSFVLLDGREENGIRLGNEELVGREVGAVLAGRPAVRAAEVVDLADPLRDGARGAFVVLAGAAADLAAVRAALGRRGVAESDCPAGVVRLRRRELVG

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	72.6
NLMSIM	60.0
AACOMP	83.0
Seqdif (SeqID)	47.8 (HKJ09959.1)
Structdif (F-Target)	5.6 (2ewn B)

ProtNLM

Name	Score
6.3.4.15	0.216
Biotin--protein ligase	0.207
Biotin--[acetyl-CoA-carboxylase] ligase	0.204
Bifunctional ligase/repressor BirA	0.192
Biotin-[acetyl-CoA carboxylase] synthetase	0.130
Biotin operon repressor	0.035