MHVNJ

Prompt

1.1.1.255

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. mannitol dehydrogenase.

AI Generated Sequence

438 AAs

MKAVHFGAGNIGRGFIGELLAKAGIAVTFADVNQPLIDALNHRGSYQVHIVGETQKVDTVSGVNAVNSMAPEDVIDAIAEVDLVTTAVGPNILDRIAPTIAKGLAKRHAANVTAPLNIIACENMVRGTTQLKGEVYALLPDEAWAEADQWVGFVDCAVDRIVPPSSATHDPLEVTVESFYEWIVDQTQMKGEIPTIPGMELTKNLMPFVERKLFTLNTGHCITAYLGKLAGHQTIRDAIADEAIRAQVKGAMQESGAVLVKRYGFDARDHAAYIQKILGRFENPYLKDDVERVGRQPLRKLGANDRLIKPLLGTIELGLPHKNVLKGIGAALLYRDSDDPQAVELAELIADKGPKGTLARLTGLDADGEVVAAVEANYLAMQQKVAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	90.5
NLMSIM	60.0
AACOMP	85.6
Seqdif (SeqID)	24.5 (ELI1523329.1)
Structdif (F-Target)	1.7 (3h2z 2)

ProtNLM

Name	Score
Mannitol-1-phosphate 5-dehydrogenase	0.567
1.1.1.17	0.423
Fructuronate reductase	0.001
Inositol-3-phosphate synthase	0.000
M1PDH	0.000
Polyol:NADP oxidoreductase	0.000