MHTOO

Prompt

6.3.4.13

Ligases. Forming carbon-nitrogen bonds. Other carbon--nitrogen ligases. phosphoribosylamine--glycine ligase.

AI Generated Sequence

473 AAs

MKILVIGSGGREHALAWKLAQSPLVTKVYCAPGNAGIAEVAELVPIAVTDIDGLVAFAKENAIDLTVVGPEAPLAAGIVDRLRAAGIRTFGPSKAAAQLEGSKGFTKDLCARYDIPTAAYGRFTDAAAAKAYVREQGAPIVIKADGLAAGKGVTVAMTLDEALAAVDDMFDGAFGAAGAEVVVEEFLDGEEASFFALCDGKTALPLGTAQDHKRVFDGDTGPNTGGMGAYSPAPVMTPEMEARTMREIVEPTVRGMAERGTPFSGVLFAGLMITDGQPKLIEYNVRFGDPECQVLMMRLKSDLLVLLNACADGTLDQMSAEWSDDHALTVVMAAKGYPGAYEKGSVIRGLDAAEADGVEIFHAGTALKDGKLVANGGRVLNVTATGATVAEAQARAYALVDRIDWPEGFCRRDIGWRAVEREKAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	93.1
NLMSIM	95.0
AACOMP	83.1
Seqdif (SeqID)	20.9 (WP_110747956.1)
Structdif (F-Target)	3.0 (2xd4 A)

ProtNLM

Name	Score
6.3.4.13	0.211
Phosphoribosylamine--glycine ligase	0.203
Phosphoribosylglycinamide synthetase	0.190
Glycinamide ribonucleotide synthetase	0.175
GARS	0.133
Phosphoribosylformylglycinamidine cyclo-ligase	0.020