MHS7W

Prompt

1.1.1.306

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. S-(hydroxymethyl)mycothiol dehydrogenase.

AI Generated Sequence

428 AAs

MSYQVRGVIARSKGEPVEITNIVIPDPGPGDAVVKIQACGVCHTDLTYREGGINDEFPFLLGHEAAGIVEAVGDGVTNVEPGDFVILNWRAVCGQCRACKRGRPHYCFDTHNATQKMTLIDGTEELTPLAIGAFAEKTLVHAGQCTKVDPDADPAAVGLCGCGVMAGLGAAINTGNVTRGDSVAVIGCGGVGDAAIAGARLAGASKIIAVDIDDKKLDWAKNFGATHTVNSKETDVVEAVRQLTGGFGADVVIDAVGRPETWKQAFYARDLAGTVVLVGVPTPTMKLELPMLDVFSRGGSLKSSWYGDCLPSRDFPMLISLYLQGRLDLDKFVTETIGLADVEEAFDKMHAGEVLRSVVVVEGSGLSERVVSLFELGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	80.3
NLMSIM	90.0
AACOMP	83.8
Seqdif (SeqID)	18.0 (WP_067068222.1)
Structdif (F-Target)	5.6 (5tnx A)

ProtNLM

Name	Score
S-(Hydroxymethyl)mycothiol dehydrogenase	0.826
1.1.1.306	0.074
Mycothiol-dependent formaldehyde dehydrogenase	0.023
Alcohol dehydrogenase	0.021
Formaldehyde dehydrogenase MscR, NAD/mycothiol-dependent / S-nitrosomycothiol reductase MscR	0.007
Zinc-dependent alcohol dehydrogenase AdhE2	0.006