MHGQ7

Prompt

1.1.1.181

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase.

AI Generated Sequence

500 AAs

MAERCLVTGGGGFLGQRIVRMLVEEGQLEEIRVFDLVPEPELRELQAAGVTVYQGDIRDRESVQRACQGISCVIFHTASVDWFGSIPHQTIYEVNVDGTQNLIEACVASGVARFIYTSSIEVAGPNSRDILNGDETLPYAEHWHDPYPYTKALAEKAVLAANGTPGGTLHTCALRPAGIFGPGDRQLMPRIIEAARNGSIKFQIGDPNNLVDWTYVENVAWAHILAARALRDPRAGRIAGQAYYITNDEPHQSFDFYNRTLSEELGYRPDPRRLPLALLWYLAHVLETVSFLISPIYNYQPLFTRYTVTLSSTTYTYSCKKAQRDLGYAPLVSWEEGKQRTIEWISQLVEEHRQRLQERGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRGRG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	84.3
NLMSIM	85.0
AACOMP	80.5
Seqdif (SeqID)	44.0 (NP_001297496.1)
Structdif (F-Target)	9.9 (3aw9 2)

ProtNLM

Name	Score
3Beta_HSD domain-containing protein	0.664
3-beta hydroxysteroid dehydrogenase/isomerase	0.027
Short-chain dehydrogenase/reductase family 42E member 1	0.017
3-beta hydroxysteroid dehydrogenase	0.015
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	0.012
3-beta hydroxysteroid dehydrogenase/isomerase family protein	0.012