MHGJ8

Prompt

3.4.22.61

Hydrolases. Acting on peptide bonds (peptidases). Cysteine endopeptidases. caspase-8.

AI Generated Sequence

500 AAs
MADFRQLLFEISEDLTVEELAALKFLSLDHVPRNKLEAIQDPMDLFEALQEKGILEEGNLSFLKELLCRINRIDLLTAHLGSSKEEMERELQVPGRAAVSPFRQLLFQISEDLTTEELASLKFLLMDHVPKNKLEAIKDMLDLFIEMEKKGILEEGNLSLLKELCFRINRIDLLTAHLDSSKEEMERELQVRGRAAVSAYDCLVICLLSGHEGSIKGTVDGKLVPIETLMTIFNNKQCPSLAGKPKLFFIQACQGDGHEKGVWVKTDDINGLEEKPITIEKSDSGSEVDAAALRKTFSWLHFEVELYKDLTAKEIRDTVNLYRSKDHKDKDCFVCCILSHGKKGIIYGVDGQEVPIYELTTSFTAQNCPSLAKGPKVFFIQACQGDAFHQGVTVEADSGQEDSQLETDARFQLDYISDEADFLLGMATLQNYVSYRSPVRGTWYIQALCQHLEYSCPRGEDILTILTAVNNEVSRKRCDRNAGKQMPQPSFTLRKKLIFP

Validation Metrics

PLDDT84.8
NLMSIM90.0
AACOMP92.9
Seqdif (SeqID)39.0 (XP_050755885.1)
Structdif (F-Target)14.0 (4ps1 D)

ProtNLM

NameScore
CASP8 protein0.622
Caspase-80.264
Caspase-8-like0.031
Caspase 80.016
Caspase 8, apoptosis-related cysteine peptidase0.006
Caspase 100.005
Designed by MP, using an AMD MI250 GPU