MHBLU

Prompt

1.1.1.27

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. L-lactate dehydrogenase.

AI Generated Sequence

500 AAs

MSTKEKLIAHVMKEEPAGSRNKVTVVGVGMVGMASAISILLKDLCDELALVDVMEDKLKGEVMDLQHGSLFLKTHKIVGKDYSVTANSKVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCIMLVVSNPVDVLTYVAWKLSGFPRHRVIGSGTCLDSARFRHLIGERLHLHPSSCHAWIVGEHGDSSVPVWSSVNVAGVSLQELNPQLGETGDKEEWKAVHKEVVDGAYEVIKLKGYTSWAIGMSVADLVESIIKNLHKVTPVSTLVKGMHGVKDDVFLSVPCVLGNSGLTDVIHMTLKPEEEKQLVKSAETLWGVQKELTLDNLIAGGGKDQVAKIIAANKVTGKKVVVVTAGVRQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCIILVVSNPVDILTYVAWKLSGFPKHRVIGSGTNLDSARFRYLMGEKLHLHPSSVHAWIVGEHGDSSVPVWSGVNVAGVSLQDLNPKLGLAPVKVKDVQDELQL

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	81.7
NLMSIM	90.0
AACOMP	90.1
Seqdif (SeqID)	35.3 (KAG8524221.1)
Structdif (F-Target)	5.8 (6bb1 D)

ProtNLM

Name	Score
1.1.1.27	0.557
L-lactate dehydrogenase	0.351
LDH-A	0.029
L-lactate dehydrogenase A chain	0.022
LDHA dehydrogenase	0.007
LDH-B	0.006