MH9TQ

Prompt

1.14.1.5

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor. Transferred entry: 1.14.13.5.

AI Generated Sequence

259 AAs
MRRLLLAGGWGAATLAKNLKKDAYDVTLVSPRNHFTFQPLLPAVATGTLEARSIVEPIRAIARKHNNFQFLGEACDIDFAAKKVVCQSLGDELTYDYLVIAAGSATNTFHTPGVKEHCFYLKEITQAQRLRHRIMLNFEKASLPTDEERRLLNFSIVIGGGPTGVELSGALHDLVNDLAKKYPKILNENLRISLIEAGRHILSAFDKRISAYAEKKLKKRGVDVLLGTRVTSVDENTVYMKDGTEIPTGMLVWATGVQA

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT91.5
NLMSIM85.0
AACOMP95.4
Seqdif (SeqID)49.3 (MQL83245.1)
Structdif (F-Target)7.2 (5kmq C)

ProtNLM

NameScore
Pyr_redox_2 domain-containing protein0.784
FAD/NAD(P)-binding domain-containing protein0.021
NADH dehydrogenase0.016
External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial0.012
External alternative NAD(P)H-ubiquinone oxidoreductase B2, mitochondrial0.012
External alternative NAD(P)H-ubiquinone oxidoreductase B1 mitochondrial0.006
Designed by MP, using an AMD MI250 GPU