MH2E2

Prompt

1.1.1.27

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. L-lactate dehydrogenase.

AI Generated Sequence

310 AAs

MKKIGIIGAGNVGASIAYNLIKQGIADEIVLIDINKDKAHAQAMDLEDATPFVGPCKIYAGDYKDLKDADIVIITAGVPQKPGETRLDLVHKNTKIFKSIIPQIMKYSFNGIFLVATNPVDILTYVTQKLSGLPKERVIGSGTVLDTARFRYLLGEHLHVDARSVHAYILGEHGDSEFAVWSLANIAGVPLQDYCKLKGHKEEDLKAIFEKVRDAAYEIINGKGATWYGIALAVARIVEAILRDENSVLPVSVLLHGYHGIKDVYLSLPAVIGANGIEKVVHLPLTDEEKEKLHKSAETLKEVYDQIELK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	91.3
NLMSIM	90.0
AACOMP	91.4
Seqdif (SeqID)	39.4 (MEE0781144.1)
Structdif (F-Target)	2.3 (2zqy D)

ProtNLM

Name	Score
L-lactate dehydrogenase	0.437
1.1.1.27	0.335
L-LDH	0.220
L-lactate dehydrogenase 2	0.001
L-lactate dehydrogenase 1	0.001
L-LDH 1	0.001