MH1SK

Prompt

2.8.1.4

Transferases. Transferring sulfur-containing groups. Sulfurtransferases. tRNA uracil 4-sulfurtransferase.

AI Generated Sequence

431 AAs

MKKKVVVAMSGGVDSAVAAYLLKEQGYEVTGIFMKNWDDSTEERGVCTWEDDYKDAKRVCEILGIPFYQVNFSKEYWERIVDYFLNEYKKGRTPNPDILCNRHIKFGAFLHYAMDLGADYIATGHYARLSFENGKVELLRKALDSNKDQSYVLSQLSQEQLKRTLFPLGELTKTEVRKIAEEAGLPTAKKKDSTGICFIGERKFKDFLAQYLKAKPGPIFDVENGKVLGKHKGMYYYTLGQRKGLGLGGKEGFLWVFVKKDVEKNEVYVTPGKNHPALYSTGLIKDDVHWISGEEPETFECEFKMRYRHSDVACTVKLLEDGRMWVTFDKPQRAITPGQFAVFYKGDECLGGGQIVETTENGKYYQFVENFRNQIGLSSFYTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Ligand/Cofactor

S-adenosylmethionine

C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O

Validation Metrics

PLDDT	81.3
NLMSIM	75.0
AACOMP	86.6
Seqdif (SeqID)	36.7 (MDK2919393.1)
Structdif (F-Target)	4.8 (2deu B)

ProtNLM

Name	Score
2.8.1.14	0.593
TRNA-specific 2-thiouridylase MnmA	0.259
TRNA-5-taurinomethyluridine 2-sulfurtransferase	0.123
2.8.1.13	0.015
Sulfurtransferase	0.001
Mitochondrial tRNA-specific 2-thiouridylase 1	0.001