MGZD1

Prompt

6.3.5.4

Ligases. Forming carbon-nitrogen bonds. Carbon--nitrogen ligases.with glutamine as amido-N-donor. asparagine synthase (glutamine-hydrolyzing).

AI Generated Sequence

621 AAs

MCGIFGGLDSTTIAALARRHPDSDGVWTDGRVVLGHRRLSILDLGEGGRQPMVDEDGSVVLVNGEIYNFRELREELEGRGHRFRTHSDTEVVLAAYEEWGEDFVRRLNGMFAVALWDRRRRRLFVARDPLGVKPLYYTTLDGTLVFGSELKALLAHPDVPREVDPLALAHYLSFQYVPPERTLFEGVHRLPPGHYLRLDRDGVRIERYWEPEFPEPHRDDEEAVARLRELLRESVARRMVADVPVGVFLSGGLDSTTIAALMARHLPEPLKTFTVGFEPGFSDEVHYARRVAEHLGTEHHEYLVTPEDVVARIPEIVWHYDEPFADSAIQPLYFVSREARRHGVKVLSGEGADELFGGYNRYHRAELLGRYDFLPRRMSRRALGEVSRPLPDRPLLRLARRSPEIRMGTTLEERYLWRAFSEDRLPERILWYRKLQGSWGYDTVEPVRRYAEGLDDPVNREMQFDLNTRLTGDILRKVDRTMAANGLEVRVPFLDHRLVEFAASIPWEMKIRGGREKYLLRQAMEGVLPKSVLDRKKQGFQVPIGRWLRGELRDWLLELLDDSRLAELGFIDRELVRRLLDEHLSGRDHYGRILWTLLMCELWHRRFVEGHVEPLRPLRIR

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	89.1
NLMSIM	95.0
AACOMP	88.6
Seqdif (SeqID)	53.7 (MBC7912287.1)
Structdif (F-Target)	11.2 (7ylz B)

ProtNLM

Name	Score
Asparagine synthase (Glutamine-hydrolyzing)	0.416
6.3.5.4	0.347
Asparagine synthetase [glutamine-hydrolyzing] 1	0.055
Asparagine synthase (Glutamine-hydrolysing)	0.054
Asparagine synthase	0.047
Asparagine synthetase [glutamine-hydrolyzing]	0.033