MGKOP

Prompt

6.2.1.45

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. E1 ubiquitin-activating enzyme.

AI Generated Sequence

500 AAs

MSDEIDEGLYSRQLYVLGHEAMKRMASSNVLIVGLKGLGVEIAKNVALAGVKSLTLYDPKPVAISDLSSQFFLQPEDVGKPRAEVTAPRVAELNAYTPVKVHESGELTEDLSQLKQYQVVVLTDTPLKDQLKIADFCHKNNIYFIIADTFGLFGSVFCDFGENFTVVDPTGENPLSGMIAGITDENGLVSALDETRHGLEDGDFVTFSEVKGMTELNGCEPRKITVKGPYTFSIGDVSGLGQYKSGGLFTQVKMPKFINFKSLTEQLKEPEFLISDFAKFDRPAQLHVGFQALHAFAETHGRLPRPMNEEDAVEVLKLAQDIAKELGEKVELDEKLIKELSYQAARGDLNPMAAFFGGIAAQEVLKAVSGKFHPIKQWLYFDSLESLPTSVERTEELCKPLGSRYDGQIAVFGKEFQDKIANLKQFLVGAGAIGCEMLKNWAMIGLGTGPKGKIYVTDMDQIEKSNLNRQFLFRPKDVGKLKSDVAAKAVQRMNPDLKGH

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	92.4
NLMSIM	70.0
AACOMP	94.1
Seqdif (SeqID)	21.6 (KAK4121739.1)
Structdif (F-Target)	16.5 (8oif A)

ProtNLM

Name	Score
UBA_e1_C domain-containing protein	0.282
Ubiquitin-activating emzyme E1	0.198
Ubiquitin-activating enzyme E1	0.168
Ubiquitin-activating enzyme E1 1	0.149
Ubiquitin activating enzyme	0.024
6.2.1.45	0.014