MGJVJ

Prompt

1.14.99.15

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. Miscellaneous. 4-methoxybenzoate monooxygenase (O-demethylating).

AI Generated Sequence

499 AAs

MRTQVAIIGAGPSGLLLGQLLHRAGIDTVILERKSRDYVLGRIRAGVLEQGMVDLLREAGVGERMHAEGLPHDGFELAFDGRRHRIDLKALTGGRVMVYGQTEVTRDLMDARDAAGGLTVYEAADVTPHDFDSDAPYVTYEKDGVTHRLDCDFIAGCDGFHGVSRKSVPADAIKTYEKVYPFGWLGVLSETPPVSHELIYANHERGFALCSMRSATRSRYYVQCPLDDKVEDWSDDRFWDELKRRLPEEAADRLVTGPSIEKSIAPLRSFVVEPMRFGRLFLCGDAAHIVPPTGAKGLNLAASDVHYLYRGLLEFYEEGSEEGIDAYSQRCLARVWKAERFSWWMTTLMHRFPDTDPFGQRIQEAELDYLVSSEAARSALAENYVGLPFEEIEEIEEIEFEEADPAIDAAELAALDFELAPAIEKSIAPLRSFVVEPMRFGRLFLCGDAAHIVPPTGAKGLNLAASDVHYLSRALREVYGDGRSAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	84.7
NLMSIM	70.0
AACOMP	92.6
Seqdif (SeqID)	20.8 (TWD45910.1)
Structdif (F-Target)	1.6 (1dob 2)

ProtNLM

Name	Score
1.14.13.2	0.561
4-hydroxybenzoate 3-monooxygenase	0.289
P-hydroxybenzoate hydroxylase	0.080
4-hydroxybenzoate hydroxylase	0.035
P-hydroxybenzoate 3-monooxygenase	0.011
Kynurenine 3-monooxygenase	0.002