MGGFH

Prompt

1.1.5.2

Oxidoreductases. Acting on the CH-OH group of donors. With a quinone or similar compound as acceptor. quinoprotein glucose dehydrogenase (PQQ, quinone).

AI Generated Sequence

794 AAs

MANNSSSRRRLLTLLTALFALLGLLLLIGGEKLAVLDGGSWYPIAGLLMLLSALLLWRRRRSALWLYAVLLFGTTMWALWEVGLDFWALTPRSDLLLFLGIWLLLPWVWRRLLGPRSGEAAALAVAVLVSGVVTWSALFNDPHEINGTLAGEATAPDAASGIADGEWHAYGRTFEGSRYSPLDQINAKNVHQLKVAWVFRTGDVKQPNDPGETYEQVTPLKVGDTLYLCTPHQRLFAIDAATGKEKWRFDPQIKTSNPQWHQTCRGVSYHEAAADKSAASAAASECPRRIFLPTNDGRLIALNAETGKLCEGFGANGQVDLRQNMGFTPAGPYEPTSPPVITGKTIVIGGSVTDNFSTREPSGVIRAFDVNTGKLVWAWDSGNPDKTALPAGEHTYTRNSPNSWAPMSYDEKLGLVYLPMGVNTPDQWGGARTPAEERYASSIVALDAATGKLRWAFQTVHHDLWDMDVPAQPTLIDITVNGDTVPAVYQPTKQGNIFVLDRNTGEPLIPVPEKPVPQGAVKGDHYSPTQPFSGLTFRPTKPLSGADMWGATMFDQLVCRVMFKSMRYEGIFTPPSEQGTLVFPGNFGMFNWGGISVDPERQVAFANPMYLPFVSKLIPRDAGNPMPPQAKGGKTESGLIQPYKGAPYGVLRNPFLSPLGFPCQKPPWGTISAVDLKTNELVWKKPVGTVRDTMPFPLHIPMPFNVGMPTLGGPIVTAGGVLFIGATLDNYLRAYDVSTGKELWQGRLPGGTQATPMTYVEKDGKQYVVITAGGHSGFGTKMGDYVVAYALPDS

Ligand/Cofactor

D-glucose

C(C1C(C(C(C(O1)O)O)O)O)O

Validation Metrics

PLDDT	74.5
NLMSIM	75.0
AACOMP	93.6
Seqdif (SeqID)	29.7 (EHQ2583219.1)
Structdif (F-Target)	16.8 (6zcw A)

ProtNLM

Name	Score
1.1.5.2	0.306
Glucose dehydrogenase	0.208
Glucose/quinate/shikimate family membrane-bound PQQ-dependent dehydrogenase	0.172
Membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family	0.102
Quinoprotein glucose dehydrogenase	0.059
Pyrroloquinoline quinone-dependent dehydrogenase	0.036