MGEJN

Prompt

6.2.1.30

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. phenylacetate--CoA ligase.

AI Generated Sequence

499 AAs

MTERERERASRDELAALQLERLRWTVRHAYDNVPFYRRKFDAAGVHPDDLRSLADLARFPFTTKADLRDNYPFGMFAVPMDQVARLHASSGTTGRPTVVGYTERDLDTWADLVARSIAAAGGRPGDMVHVAYGYGLFTGGLGAHYGAERLGCTVIPMSGGMTERQVQLIRDFGPEIIMVTPSYMLTILDEMERQGMDPRRTSLRIGIFGAEPWTNAMRREIEARFGMDAVDIYGLSEVMGPGVAQECVETKDGLHIWEDHFYPEIIDPVTGEVLPDGEMGELVFTSLTKEAMPVIRYRTRDLTRLLPGTARTMREMGKITGRSDDMIIIRGVNVFPTQIEEIVLRQPGLAPHYQIVLDREGHMDRLEVRVEVRPEHVPAAAAAAARERLHRHIKNTIGVTVRVEVVDPGTIERSEGKARRVVDLRPKVDGGRPVIVERIEAVMAADPERGEVVAAERARLQAHIKNQIGVTVPVEVVDPEGLERSEGKARRVVDNRPLK

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	87.3
NLMSIM	70.0
AACOMP	90.5
Seqdif (SeqID)	21.9 (WP_185042261.1)
Structdif (F-Target)	4.8 (2y27 A)

ProtNLM

Name	Score
Phenylacetyl-CoA ligase	0.347
Phenylacetate-coenzyme A ligase	0.339
6.2.1.30	0.296
Phenylacetate--CoA ligase	0.003
Phenylacetate-CoA ligase	0.003
AMP-binding protein	0.001