MGDSI

Prompt

1.1.1.277

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 3beta-hydroxy-5beta-steroid dehydrogenase.

AI Generated Sequence

385 AAs

MKVLVTGGCGFLGAHIVERLLARGDEVRIAVDRRRPEPELAGVTVVQGDLTDPAAVAAACAGVDTVIHTASKPDVSGWDYALHYRVNVEGTRNVIDACVAAGVRALVYTSSASVVFDGADLVNVDESLPYPETKQMDAYTETKAIAEALVLAANGDGLLTCALRPMGIFGRGDPQLVQRLVDVARNGSLKFQVGDNKNLVDFTYVGNAAWAHVLAAEALAGDGAAFFITNGEPVYFWEFARSVWEAHGYEPRTAVALPLPLAYGLASLVSEWVWLLLPLGKVEPALTRFRVEALCTTHYYDIAKARRDLGYAPQVGMEEGIRRTVEWFRGHEAAKAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	94.3
NLMSIM	85.0
AACOMP	82.7
Seqdif (SeqID)	52.6 (KAJ6262515.1)
Structdif (F-Target)	10.6 (6kvc 2)

ProtNLM

Name	Score
3Beta_HSD domain-containing protein	0.689
NAD(P) dependent steroid dehydrogenase-like	0.019
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	0.016
NAD(P)-dependent steroid dehydrogenase-like protein	0.013
3-beta hydroxysteroid dehydrogenase/isomerase family-domain-containing protein	0.012
NAD(P)-dependent steroid dehydrogenase-like	0.009