MGDBC

Prompt

1.5.1.36

Oxidoreductases. Acting on the CH-NH group of donors. With NAD(+) or NADP(+) as acceptor. flavin reductase (NADH).

AI Generated Sequence

463 AAs

MKKILVVGAGFAGLNAARRLGRPDVDITLVARNNFHLFQPLLYEVATGILSSADIAWPLREHFRRHNVLLFQGAEVAGIDRAAGTVTLADGVELAYDTLVIAAGSRSNYFGIPGWEAHAPGLKSLDDALLIRRHILAAFERAELPTDPAERAALLTTVIVGGGPTGVELAGAIAELTHRTLADYFRVIDPAAARVTLIEAGPRILPAFADRLSAYAQRQLERLGVEIRLGTAVTACAADGVTTKDGAEIAAQTLVWAAGVQASAVGAALGLETDRAGRVLVDPALTVPGHPEVFAVGDTASALDGGYPVGPVAPAAMQQGRHAAAAIRARLAGRPPAGFRYRDLGALATIGRFAAVADLGRLRLAGLPAWLWKAAVHLYLLIGFRNRLAVLLDWTLAYLTWDRSARLITGGRRAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT	93.8
NLMSIM	60.0
AACOMP	80.5
Seqdif (SeqID)	40.8 (WP_325277910.1)
Structdif (F-Target)	6.7 (4nwz A)

ProtNLM

Name	Score
NADH dehydrogenase	0.281
NAD(P)/FAD-dependent oxidoreductase	0.196
Pyridine nucleotide-disulfide oxidoreductase	0.070
FAD-dependent oxidoreductase	0.069
1.6.99.3	0.066
1.6.99.-	0.051