MGATQ

Prompt

5.3.2.8

Isomerases. Intramolecular oxidoreductases. Interconverting keto- and enol-groups. 4-oxalomesaconate tautomerase.

AI Generated Sequence

66 AAs
MPIINIKTTGGSTDEQKKAIIEGITKAVVDNLGKPAESITVIIEEMPKDNWGKGGELVSEQRRALK

Ligand/Cofactor

4-oxalomesaconate

C(C(=CC(=O)O)C(=O)O)C(=O)C(=O)O

Validation Metrics

PLDDT92.6
NLMSIM60.0
AACOMP85.0
Seqdif (SeqID)47.5 (WP_012676134.1)
Structdif (F-Target)2.6 (4fdx B)

ProtNLM

NameScore
Tautomerase0.580
5.3.2.-0.413
4-oxalocrotonate tautomerase0.002
2-hydroxymuconate tautomerase0.001
5.3.2.60.001
4-oxalocrotonate tautomerase family enzyme0.000
Designed by MP, using an AMD MI250 GPU