MG52U

Prompt

1.3.1.96

Oxidoreductases. Acting on the CH-CH group of donors. With NAD(+) or NADP(+) as acceptor. Botryococcus squalene synthase.

AI Generated Sequence

500 AAs

MGKLLELLLHPEEFKAIVQWKLFWHPAPHKRDEKKESPHLKRCYKYLDQTSRSFAAVIQELHGELRDVVCIFYLVLRGLDTIEDDMTIPLEVKKPLLRNFHQYLMQDGWTMNDNGPKEKDRQVLVDFHNIISEFRNMKPQYHVIIADITDKMGNGMADYACNETLNGVNTIEDYDLYCHYVAGLVGEGLTRLFVEAKLANPALAQRPELANSMGLFLQKTNIIRDYREDNDEGRRFWPREIWSKHVDEFGDLFKPENYELALQCNSEMVLNALKHAEDCLFYMAALRNQSVFNFCAIPQSMAIATLELCFQNPMVFQRNVKIRKGQACALIMESTQNLQVVCDIFRRYARRIHKKSNPKDPNFLKISIACGRIEQKIETIFPSQPRAKLAARTGEPVPEEARKAMEEAASWDTLYFLMAVGGVLLIIITGIMLIAAWLLGARFDLAWQEIKLGNFRPPTGGIQELLGGVIEKYEELPKEKKKEKEKEKEKEKEKEKEKEK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	87.1
NLMSIM	75.0
AACOMP	92.2
Seqdif (SeqID)	34.1 (ODM24304.1)
Structdif (F-Target)	2.8 (7wgi A)

ProtNLM

Name	Score
Squalene synthase	0.502
2.5.1.21	0.458
Farnesyl-diphosphate farnesyltransferase	0.015
Isoprenoid synthase domain-containing protein	0.003
SQS	0.002
FPP:FPP farnesyltransferase	0.002