MF9PA

Prompt

1.13.11.6

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. 3-hydroxyanthranilate 3,4-dioxygenase.

AI Generated Sequence

161 AAs
MLEPVFNFRKWIEENPHLEPPPVNQRCWDYGLFNVMVTGPNGTRDHHEAPGEEWFYQLEGDMLLRVVENGPFRHDIIRNGENFLLPPRIPHSPMRFADTVGLVIEHERLPGTEIGDLRWYCQSCNTVVKEPVFLCDLIDTLQKVEERFQNDPSQFRTCRNP

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT71.1
NLMSIM95.0
AACOMP87.3
Seqdif (SeqID)49.1 (KAJ3320235.1)
Structdif (F-Target)11.8 (1zvf B)

ProtNLM

NameScore
3-hydroxyanthranilate 3,4-dioxygenase0.266
1.13.11.60.203
3-hydroxyanthranilic acid dioxygenase0.147
3-hydroxyanthranilate oxygenase0.139
HAD0.126
3-HAO0.091
Designed by MP, using an AMD MI250 GPU